Table 7. Likelihood of significant coronary artery disease in patients with symptoms suggesting unstable angina

High likelihood           Intermediate likelihood   Low likelihood
(e.g., 0.85-0.99)         (e.g., 0.15-0.84)         (e.g., 0.01-0.14)
___________________________________________________________________________
Any of the high or        Absence of high           Absence of intermediate
following features:       likelihood features and   likelihood features but
                          any of the following:     may have:
___________________________________________________________________________
History of prior MI or    Definite angina: males    Chest pain classified
sudden death or other     <60 or females            as probably not angina
known history of CAD      <70 years of age
Definite angina: males    Probable angina: males    One risk factor other
>e;60 or females            >e;60 or females            than diabetes
>e;70 years of age          >e;70 years of age
Transient hemodynamic     Chest pain probably not   T-wave flattening
or ECG changes during     angina in patients with   or inversion <1 mm
pain                      diabetes                  in leads with dominant
                                                    R waves
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Variant angina (pain      Chest pain probably not   Normal ECG
with reversible           angina and two or three
ST-segment                risk factors other than
elevation)                diabetes[1]
___________________________________________________________________________
ST segment elevation or   Extracardiac vascular
depression >e;1 mm      disease
Marked symmetrical        ST depression 0.05 to 1
T- wave inversion   mm
in multiple precordial
leads
___________________________________________________________________________
                          T-wave inversion
                          >e;1 mm in leads with
                          dominant R-waves
___________________________________________________________________________
[1] Coronary artery disease risk factors include diabetes,
smoking, hypertension, and elevated cholesterol.
Note: Estimation of the likelihood of significant coronary artery
disease is a complex, multivariable problem that cannot be fully
specified in a table such as this. Therefore, the table is meant
to illustrate major relationships rather than offer rigid
algorithms.