PAEDIATRIC ANAESTHESIA

Digoxin


                 Saturation dose (yg/kg)    Maintenance dose (yg/kg/d)
                     iv          po               iv          po
Preterm neonate    20 - 30     30 - 40          5 - 8       8 - 10     
Term neonate       30 - 35     40 - 50          8 - 10      10 - 12    
1 Mo. - 2 yr.      40 - 45     50 - 60         10 - 12      12 - 15    
2 - 5 Years        30 - 35     30 - 50          8 - 10      10 - 12    
> 5 Years          20 - 30     30 - 40          6 - 8       8 - 10

For quick digitilisation: half dose initially, 1/4 after 4 - 8 hours,
a further 1/4 after 4 - 8 hours, another 1/4 after 8 - 16 hours.

Effective Digoxin - Serum level for babies and children :
                            0.9 - 3.7 ng/ml

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betzendoerfe@ubaclu.unibas.ch
last update 03-30-95