Normal Values / Serum Reference Values

PLASMA LEVEL

Drugs etc.                normal/              toxic        potentially lethal
                          therapeutic          mg/l                mg/l

Acetazolamide            10 - 15                                               
Aminophylline            10 - 20               20                              
Amiodarone                1 - 2.5 g/ml                                             
Amitriptyline            50 - 200 g/l         400 g/l            10 - 20       
Amphetamine              20 - 30 g/l                                             
Carbamazepine             4 - 8                12                              
Quinidine                 2 - 5 g/ml                                              
Chloral hydrate               10              100                  250         
Chlordiazepoxide          1 - 2                 6                   20          
Chlorpromazine             0.3                1 - 2                3 - 12        
CO                      1% des SaO2          15 - 30 %              50 %         
Codeine                   25 g/l                                                
Cyanide                    0.15                                      5          
Desipramine            0.59 - 1.4                                 10 - 20       
Diazepam                0.5 - 2.5             5 - 20                50          
Digitoxin                20 - 35 g/l                               320 g/l       
Digoxin                   1 - 2 g/l           2 - 9 g/l                          
Diphenhydramine              5                 10                              
Diphenylhydantoin        10 - 18                                               
Disopyramide              2 - 5 g/ml                                              
Ethosuximide             40 - 100                                               
Gentamicin                5 - 8              10 - 12                           
Lidocaine                 2 - 5                 6                              
Lithium                 0.8 - 1.2 mmol/l    1.5 mmol/l            4 mmol/l       
Methanol                                      200                   890         
Methosuximide            20 - 35                                               
Mexiletin               0.8 - 2                                               
Paracetamol               5 - 25               30                              
Phenacetin                5 - 25               30                   400         
Phenobarbital            15 - 30             40 - 70               80 - 150       
Phenylbutazone             100                                                 
Phenytoin                 8 - 20               30                   100         
Primidone                 6 - 15                                                
(Mysoline)                                                                     
Procainamide              4 - 10 g/ml                                             
Propranolol           0.025 - 0.1                                   8 - 12        
Salicylate              100 - 250           350 - 400               500         
Theophylline              2 - 10               20                              
Tobramycin                5 - 8              10 - 12                           
Tolbutamide              53 - 96                                               
Valproate                40 - 80                                               
Verapamil              > 100ng/ml